4 Best Stool Softeners in 2025
Constipation is a common issue affecting millions, often caused by diet, dehydration, medications, or lifestyle factors. Stool softeners are over-the-counter remedies that work by drawing water into the stool, making it easier to pass without straining or causing harsh side effects like cramping. Unlike stimulant laxatives, they focus on hydration rather than forcing bowel movements, making them ideal for occasional use, post-surgery recovery, or pregnancy. 22 According to a 2025 pharmacist survey by U.S. News & World Report, the top options prioritize gentleness, effectiveness, and minimal side effects. 32 Here are the four best stool softeners based on expert rankings, user reviews, and clinical reliability.
1. Colace Regular Strength (Docusate Sodium 100mg)
4.6 out of 5 Ratings
Colace has long been the gold standard for stool softeners, earning the #1 spot in pharmacist rankings for its proven track record in providing gentle, reliable relief. This capsule form allows water and fats to penetrate the stool, softening it within 12 to 72 hours without stimulating the intestines.
Key Benefits:
- Doctor-recommended for nearly 60 years.
- Stimulant-free, reducing risks of diarrhea or cramps.
- Suitable for adults, children over 2, and those avoiding strain (e.g., after childbirth).
Pros: Easy to swallow, FSA-eligible, and widely available in 60- or 100-count bottles (around $10-15).
Cons: May take up to 3 days for full effect; not ideal for severe, chronic constipation.
How to Use: Take 1-2 capsules daily with a full glass of water, preferably at bedtime. Consult a doctor if symptoms persist beyond a week.
2. MiraLAX (Polyethylene Glycol 3350)
4.8 out of 5 Ratings
As an osmotic laxative that doubles as a top-tier stool softener, MiraLAX ranks highly for its ability to hydrate stool thoroughly and promote regular movements over 1-3 days. It’s flavorless powder mixes easily into beverages, making it user-friendly for daily routines.
Key Benefits:
- Fewer side effects than stimulants; well-tolerated for long-term use.
- Effective for softening hard stools caused by medications or low-fiber diets.
- FSA-eligible and safe for kids 17 pounds and up.
Pros: Unflavored and versatile (dissolves in coffee, juice, or water); a 17-dose bottle costs about $20.
Cons: Slower onset (24-72 hours); not suitable for those with kidney issues without medical advice.
How to Use: Mix one capful (17g) in 4-8 oz of liquid once daily. It’s gentle enough for ongoing use but stop if no improvement after 7 days.
3. Dulcolax Stool Softener (Docusate Sodium 100mg)
4.7 out of 5 Ratings
Dulcolax’s gentle relief formula is a pharmacist-favorite for its softgel design and quick hydration of dry stools, often working in 12-72 hours. It’s stimulant-free and focuses on comfort, earning praise for post-op or pregnancy use.
Key Benefits:
- No. 1 doctor-recommended docusate ingredient.
- Helps prevent hemorrhoids by reducing straining.
- Easy-to-swallow gel caps for discreet daily dosing.
Pros: Affordable (25-count around $8) and effective without bloating; great for travel packs.
Cons: Results can vary; avoid in children under 2 or with prolonged use without guidance.
How to Use: Adults take 1-3 softgels daily with water. Pair with increased fiber intake for best results.
4. Amazon Basic Care Stool Softener Laxative
4.6 out of 5 Ratings
Amazon Basic Care Stool Softener Laxative, Docusate Sodium 100 mg, Softgels, for Constipation Relief, 100 Count (Pack of 2).
Rounding out the top picks, Amazon Basic Care Stool Softener Laxative offers straightforward softening with a trusted formula that’s gentle on the gut and effective for everyday constipation. It’s a solid choice for those seeking an affordable, no-frills option that hydrates stool reliably.
Key Benefits:
- Promotes comfortable bowel movements without urgency.
- FSA-eligible and suitable for ages 12 and up.
- Compact capsules for on-the-go relief.
Pros: Budget-friendly (100-count under $10); minimal side effects like mild stomach upset.
Cons: Less potent for very hard stools; may require consistent use for optimal softening.
How to Use: Take 1-3 capsules up to three times daily with plenty of fluids. Not for long-term dependency.
Final Thoughts
These four stool softeners—Colace, MiraLAX, Dulcolax, and Phillips’—stand out for their safety, efficacy, and pharmacist endorsements, but they’re not one-size-fits-all. 32 Always prioritize lifestyle changes like drinking 8+ glasses of water daily, eating fiber-rich foods (fruits, veggies, whole grains), and exercising. If constipation lasts more than a week, involves pain, or accompanies blood in stool, see a healthcare provider to rule out underlying issues. Pregnant individuals or those on medications should consult a doctor before starting any new regimen. With the right choice, relief is just a soft stool away!
