5 Best Supplements for Prostate Health in 2025

Prostate health is a growing concern for men as they age, with conditions like benign prostatic hyperplasia (BPH), prostatitis, and prostate cancer affecting millions worldwide. While lifestyle changes, diet, and medical treatments play key roles, supplements can offer supportive benefits by reducing inflammation, lowering PSA levels, and potentially slowing disease progression. Based on recent research from reputable sources, here are the five top supplements backed by evidence for prostate support. Always consult a healthcare provider before starting any supplement, as they may interact with medications or have varying effects based on individual health.

1. Saw Palmetto

Saw palmetto is an extract from the berries of the Serenoa repens plant, traditionally used for urinary tract symptoms. It works by inhibiting the enzyme 5-alpha-reductase, which converts testosterone to dihydrotestosterone (DHT), a hormone linked to prostate enlargement.

Benefits: It may alleviate BPH symptoms like frequent urination and weak urine flow, and some studies suggest anti-inflammatory effects similar to prescription drugs. A 2022 review found it modestly effective for urinary symptoms in BPH.

Evidence: Mixed but promising for BPH; a proprietary extract showed benefits comparable to alpha-blockers, though larger reviews conclude no major impact on prostate cancer risk. Products like Havasu Nutrition Saw Palmetto and NOW Pygeum and Saw Palmetto are popular formulations.

Dosage: 160–320 mg daily of standardized extract.

Side Effects: Generally safe; mild stomach upset or headaches possible.

2. Beta-Sitosterol

Beta-sitosterol is a plant sterol found in nuts, seeds, and vegetables, often combined with other prostate-supporting ingredients in supplements.

Benefits: It helps reduce urinary symptoms associated with BPH by improving bladder emptying and urine flow, while offering anti-inflammatory properties.

Evidence: Strong for BPH symptom relief; studies show it lowers PSA levels and supports urinary health. Featured in top picks like Life Extension PalmettoGuard and NOW Supplements Beta-Sitosterol Plant Sterols.

Dosage: 60–130 mg daily.

Side Effects: Rare; may cause mild digestive issues.

3. Lycopene

Lycopene is a powerful antioxidant carotenoid abundant in tomatoes, watermelon, and pink grapefruit, known for its red pigmentation.

Benefits: It combats oxidative stress and inflammation in the prostate, potentially lowering PSA levels and reducing cancer risk.

Evidence: Epidemiological studies link higher intake to decreased prostate cancer risk, with some trials showing reduced tumor growth in preclinical models. Interventional studies report improved PSA velocity post-supplementation, though results are inconsistent for cancer prevention.

Dosage: 10–30 mg daily, ideally from cooked tomato sources for better absorption.

Side Effects: Well-tolerated; minor GI upset at high doses.

4. Zinc

Zinc is an essential mineral crucial for immune function and cell growth, with high concentrations naturally found in the prostate gland.

Benefits: It supports prostate cell health and semen production, potentially reducing BPH and cancer risks linked to deficiency.

Evidence: Population studies associate low zinc levels with higher prostate cancer risk, but supplementation benefits are uncertain—excess may increase aggressive cancer odds. RDA is 11 mg for adult men.

Dosage: 15–30 mg daily, not exceeding 40 mg to avoid copper interference.

Side Effects: Nausea or reduced mineral absorption at high doses.

5. Green Tea Extract (EGCG)

Green tea extract, rich in catechins like epigallocatechin gallate (EGCG), provides potent antioxidant effects.

Benefits: It may inhibit prostate cell proliferation, reduce PSA levels, and lower inflammation, supporting both BPH and cancer prevention.

Evidence: Reviews show three or more cups daily (or 400–600 mg EGCG) linked to reduced risk; trials in high-risk men (e.g., HGPIN) demonstrate delayed progression, though results vary. Preclinical data supports anti-cancer pathways.

Dosage: 200–400 mg EGCG daily.

Side Effects: Mild GI issues; liver monitoring advised for high doses.

Final Thoughts

These supplements—saw palmetto, beta-sitosterol, lycopene, zinc, and green tea extract—stand out for their evidence-based potential in promoting prostate health, particularly for managing BPH symptoms and supporting preventive care. However, evidence is often mixed, with stronger support for symptom relief than cancer prevention. Prioritize a balanced diet rich in these nutrients, regular screenings, and professional medical advice to tailor a regimen. As research evolves into 2025 and beyond, staying informed can empower better decisions for long-term wellness.