5 Best Antacids for Acid Reflux in 2025

Acid reflux, also known as gastroesophageal reflux disease (GERD), is a common condition where stomach acid flows back into the esophagus, causing symptoms like heartburn, regurgitation, and discomfort. While lifestyle changes and prescription medications play a key role in long-term management, over-the-counter (OTC) antacids offer fast, temporary relief by neutralizing excess stomach acid. In 2025, these products remain popular for occasional flare-ups, but they’re not a cure and shouldn’t be used daily without medical advice. Based on expert recommendations from sources like GoodRx, Mayo Clinic, and WebMD, here are the top five antacids for acid reflux, selected for their effectiveness, availability, and user feedback.

1. Tums (Calcium Carbonate)

Tums is a classic chewable antacid that’s widely available in various flavors and forms, including tablets, soft chews, and gummies. It works by directly neutralizing stomach acid on contact, providing relief in as little as seconds.

Pros:

• Extremely fast-acting, often within minutes.
• Affordable and portable.
• Doubles as a calcium supplement.

Cons:

• Short duration of relief (about 1 hour).
• May cause constipation or acid rebound with frequent use.
• Can interfere with absorption of other medications if taken too closely together.

Best for occasional heartburn after meals. Take 2-4 tablets as needed, but not more than 10 per day.

2. Gaviscon (Aluminum Hydroxide, Magnesium Carbonate, and Alginic Acid)

Gaviscon stands out for its unique “raft-forming” technology, where it creates a floating foam barrier on top of stomach contents to block acid from refluxing into the esophagus. Available as liquid or chewable tablets.

Pros:

• Longer-lasting protection (up to 4 hours) compared to traditional antacids.
• Specifically effective for GERD symptoms like post-meal reflux.
• Reduces acid pocket exposure in the esophagus.

Cons:

• Tablets must be chewed thoroughly; liquid form may taste chalky.
• Potential for mild side effects like constipation or diarrhea.
• Higher sodium content, so use caution if on a low-sodium diet.

Ideal for those with frequent reflux episodes, especially at night. Dosage: 2-4 tablets or 10-20 mL liquid after meals and bedtime.

3. Mylanta Maximum Strength (Aluminum Hydroxide, Magnesium Hydroxide, and Simethicone)

This liquid antacid combines acid neutralizers with simethicone to tackle both heartburn and associated gas or bloating. It’s a go-to for comprehensive symptom relief.

Pros:

• Works on contact for quick action (faster than tablets).
• Includes gas relief, making it great for indigestion with bloating.
• Balanced formula minimizes side effects like extreme constipation or diarrhea.

Cons:

• Short-term relief (1-2 hours).
• Liquid form may be less convenient for on-the-go use.
• Not suitable for long-term daily use without doctor approval.

Perfect for acid reflux accompanied by gas. Shake well and take 10-20 mL as needed, up to 4 times daily.

4. Rolaids Ultra Strength (Calcium Carbonate and Magnesium Hydroxide)

Rolaids offers a dual-action chewable tablet that neutralizes acid while the magnesium helps counteract potential constipation from the calcium.

Pros:

• Rapid relief for heartburn and sour stomach.
• Chewable and flavored for easy use.
• Provides a balance to avoid common antacid side effects.

Cons:

• Limited duration (around 1 hour).
• May cause loose stools if overused due to magnesium.
• Potential for acid rebound similar to other calcium-based options.

Suited for quick relief during social events or meals. Chew 2 tablets as symptoms occur, not exceeding 12 per day.

5. Maalox Advanced Maximum Strength (Aluminum Hydroxide and Magnesium Hydroxide)

Maalox is a liquid antacid that swiftly neutralizes acid and is often recommended for upset stomach alongside reflux. Some formulations include simethicone for extra gas relief.

Pros:

• Fast absorption and onset in liquid form.
• Effective for acid indigestion and general stomach discomfort.
• Widely available and inexpensive.

Cons:

• Can lead to diarrhea (magnesium) or constipation (aluminum) with prolonged use.
• Short relief window.
• Avoid in kidney issues due to mineral buildup risk.

Great for acute episodes of reflux with nausea. Take 10-20 mL between meals or at bedtime, up to 4 times daily.

Final Thoughts

These antacids are excellent for short-term relief of acid reflux symptoms, but if you experience heartburn more than twice a week, it could signal underlying GERD or other issues—consult a healthcare provider for personalized advice. Combine them with lifestyle tweaks like elevating your head while sleeping, avoiding trigger foods (e.g., spicy or fatty items), and eating smaller meals. Always check for interactions with other medications and follow dosage instructions to avoid side effects like mineral imbalances. Stay proactive about your digestive health in 2025!